منابع مشابه
View from the Pennines: Systems Biology
A large number of trees were planted in the eld at the back of our garden about ten years ago. Some are relatively fast growing (silver birch, larch, some rs) and others less so (oak, horse chestnut). The planting was quite well thought out, and in the next few years the faster growing species will need to be thinned, creating space for the slowly maturing giants. This process has been somethin...
متن کاملA systems view of mRNP biology.
Gene expression occurs through a complex mRNA-protein (mRNP) system that stretches from transcription to translation. Gene expression processes are increasingly studied from global perspectives in order to understand their pathways, properties, and behaviors as a system. Here we review these beginnings of mRNP systems biology, as they have emerged from recent large-scale investigation of mRNP c...
متن کاملEvolution and RNA relics. a systems biology view.
The genetic code has evolved from its initial non-degenerate wobble version until reaching its present state of degeneracy. By using the stereochemical hypothesis, we revisit the problem of codon assignations to the synonymy classes of amino-acids. We obtain these classes with a simple classifier based on physico-chemical properties of nucleic bases, like hydrophobicity and molecular weight. Th...
متن کاملA systems biology view of blood vessel growth and remodelling
Blood travels throughout the body in an extensive network of vessels - arteries, veins and capillaries. This vascular network is not static, but instead dynamically remodels in response to stimuli from cells in the nearby tissue. In particular, the smallest vessels - arterioles, venules and capillaries - can be extended, expanded or pruned, in response to exercise, ischaemic events, pharmacolog...
متن کاملSystems biology and the biology of systems.
When I sit down to write an editorial for Physiology, I flatter myself that the two or three people who will ultimately read it want to hear my thoughts on a “big” topic. It strikes me that, within the rarefied realm of academic biology, there few bigger topics, or at least few topics more all encompassing in their scope, than Systems Biology. Perhaps it is the ambiguity inherent in its name th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: EMBO reports
سال: 2009
ISSN: 1469-221X,1469-3178
DOI: 10.1038/embor.2009.124